Article
Genetics and genomics of primary biliary cirrhosis.
Clinics in liver disease - 1 May 2008
Juran Brian D, Lazaridis Konstantinos N
Abstract excerpt
The etiologic and pathogenic factors contributing to primary biliary cirrhosis (PBC) development, progression, response to treatment, and outcome remain a mystery. Recognition of the genomic regions harboring risk factors is hindered by the rarity and late onset of PBC. Recent advancements in genomics hold promise for understanding, prevention, and therapy of PBC. Large registries and biospecimen repositories of...
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