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Article

Polymorphisms of IL12RB2 May Affect the Natural History of Primary Biliary Cholangitis: A Single Centre Study.

Journal of immunology research - 1 Jan 2017

Wasik Urszula, Wunsch Ewa, Norman Gary L, Rigopoulou Eirini I, Bogdanos Dimitrios P, Milkiewicz Piotr, Milkiewicz Małgorzata

Abstract excerpt

Background. Recent GWAS in primary biliary cholangitis (PBC) showed strong associations with SNPs located within interleukin-12 receptor (IL12R) beta-2 (IL12RB2) gene. Aims. We assessed whether genetic variation of IL12RB2 is associated with laboratory and clinical features of PBC. Methods. Genomic DNA was isolated from 306 patients with PBC and 258 age/gender-matched controls. PBC-specific anti-mitochondrial...

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Identifiers

PMID: 28299343
DOI: 10.1155/2017/2185083
PMCID: PMC5337364

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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