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Article

BSEP and MDR3 haplotype structure in healthy Caucasians, primary biliary cirrhosis and primary sclerosing cholangitis.

Hepatology (Baltimore, Md.) - 1 Mar 2004

Pauli-Magnus Christiane, Kerb Reinhold, Fattinger Karin, Lang Thomas, Anwald Birgit, Kullak-Ublick Gerd A, Beuers Ulrich, Meier Peter J

Abstract excerpt

Primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC) are characterized by a cholestatic pattern of liver damage, also observed in hereditary or acquired dysfunction of the canalicular membrane transporters bile salt export pump (BSEP, ABCB11) and multidrug resistance protein type 3 (MDR3, ABCB4). Controversy exists whether a genetically determined dysfunction of BSEP and MDR3 plays a...

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Share to ATP Binding Cassette Transporter, Subfamily B
Share to ATP Binding Cassette Transporter, Subfamily B, Member 11

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Cholangitis, Sclerosing

Share to Liver Cirrhosis, Biliary

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Source

Identifiers

PMID: 14999697
DOI: 10.1002/hep.20159

Genes

ABCB11
ABCB4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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