Article
Interval-specific congenic lines reveal quantitative trait Loci with penetrant lyme arthritis phenotypes on chromosomes 5, 11, and 12.
Infection and immunity - 1 Aug 2009
Ma Ying, Miller Jennifer C, Crandall Hillary, Larsen Eric T, Dunn Diane M, Weiss Robert B, Subramanian Meenakumari, Weis John H, Zachary James F, Teuscher Cory, Weis Janis J
Abstract excerpt
The observation that Borrelia burgdorferi-induced arthritis is severe in C3H mice and milder in C57BL/6 (B6) mice has allowed a forward genetics approach for the identification of genetic elements that regulate the arthritis response. Quantitative trait loci (QTL) on five chromosomes (Chr) were i...
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