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Article

A genome scan using a novel genetic cross identifies new susceptibility loci and traits in a mouse model of rheumatoid arthritis.

Journal of immunology (Baltimore, Md. : 1950) - 1 Nov 2000

Otto J M, Chandrasekeran R, Vermes C, Mikecz K, Finnegan A, Rickert S E, Enders J T, Glant T T

Abstract excerpt

Proteoglycan-induced arthritis (PGIA) is a murine model for rheumatoid arthritis (RA) both in terms of its pathology and its genetics. PGIA can only be induced in susceptible mouse strains and their F(2) progeny. Using the F(2) hybrids resulting from an F(1) intercross of a newly identified susce...

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Share to Arthritis, Rheumatoid
Share to Genome
Share to Injections, Intraperitoneal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Inbred BALB C

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Share to Quantitative Trait, Heritable

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Source

Identifiers

PMID: 11046062
DOI: 10.4049/jimmunol.165.9.5278

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11046062-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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