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Article

T helper phenotype and genetic susceptibility in experimental Lyme disease.

1 Mar 1995

Abstract excerpt

Infection of inbred mice with Borrelia burgdorferi results in strain-specific variation in the severity of pathogen-induced arthritis: BALB/c mice develop only mild disease whereas C3H/HeJ mice develop severe arthritis. The immunologic basis for varying host susceptibility has yet to be defined. We modified experimental Lyme disease to facilitate measurement of antigen-specific cytokine production in resistant...

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Identifiers

PMID: 7869043
DOI: 10.1084/jem.181.3.1251

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Source receipt: pubmed, retrieved 7 Sept 2026.

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