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Article

Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation.

The Journal of cell biology - 1 Jun 2009

Gu Bingnan, Sun Peng, Yuan Yuanyang, Moraes Ricardo C, Li Aihua, Teng Andy, Agrawal Anshu, Rhéaume Catherine, Bilanchone Virginia, Veltmaat Jacqueline M, Takemaru Ken-Ichi, Millar Sarah, Lee Eva Y-H P, Lewis Michael T, Li Boan, Dai Xing

Abstract excerpt

Recent studies have unequivocally identified multipotent stem/progenitor cells in mammary glands, offering a tractable model system to unravel genetic and epigenetic regulation of epithelial stem/progenitor cell development and homeostasis. In this study, we show that Pygo2, a member of an evolutionarily conserved family of plant homeo domain-containing proteins, is expressed in embryonic and postnatal mammary...

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Identifiers

PMID: 19487454
DOI: 10.1083/jcb.200810133
PMCID: PMC2711593

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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