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Article

pygopus 2 has a crucial, Wnt pathway-independent function in lens induction.

Development (Cambridge, England) - 1 May 2007

Song Ni, Schwab Kristopher R, Patterson Larry T, Yamaguchi Terry, Lin Xinhua, Potter Steven S, Lang Richard A

Abstract excerpt

Drosophila Pygopus was originally identified as a core component of the canonical Wnt signaling pathway and a transcriptional coactivator. Here we have investigated the microophthalmia that arises in mice with a germline null mutation of pygopus 2. We show that this phenotype is a consequence of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17428831
DOI: 10.1242/dev.001495

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17428831-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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