Article
Abnormal expression of Pygopus 2 correlates with a malignant phenotype in human lung cancer.
BMC cancer - 16 Jul 2013
Liu Yang, Dong Qian-Ze, Wang Si, Fang Chang-Qing, Miao Yuan, Wang Liang, Li Ming-Zhu, Wang En-Hua
Abstract excerpt
BACKGROUND: Pygopus 2 (Pygo2) is a Pygo family member and an important component of the Wnt signaling transcriptional complex. Despite this data, no clinical studies investigating Pygo2 expression in lung cancer have yet been reported. METHODS: In the present study, the expression patterns of Pygo2 were evaluated by immunochemistry in 168 patients with non-small cell lung cancer (NSCLC). We used small interfering...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
