Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Runx2 contributes to the regenerative potential of the mammary epithelium

22 Oct 2015

Abstract excerpt

Although best known for its role in bone development and associated structures the transcription factor RUNX2 is expressed in a wide range of lineages, including those of the mammary gland. Previous studies have indicated that Runx2 can regulate aspects of mammary cell function and influence the properties of cancer cells. In this study we investigate the role of Runx2 in the mammary stem/progenitor population...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Metabolism and Diseases
Share to Cancer Cells and Metastasis
Share to dental development and anomalies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26489514
DOI: 10.1038/srep15658

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Runx2 contributes to the regenerative potential of the mammary epitheliumPMID 26489514Read ↗

RUNX2 in mammary gland development and breast cancerSemantic proximity Read ↗

New insights into the role of Runx1 in epithelial stem cell biology and pathologySemantic proximity Read ↗

A role for Runx2 in normal mammary gland and breast cancer bone metastasisSemantic proximity Read ↗

RUNX2 in subtype specific breast cancer and mammary gland differentiationSemantic proximity Read ↗

RUNX3 in Stem Cell and Cancer Biology.Semantic proximity Read ↗

Runx Genes in Breast Cancer and the Mammary Lineage.Semantic proximity Read ↗

Runx2 in normal tissues and cancer cells: A developing storySemantic proximity Read ↗

Suppression of Breast Cancer Stem Cells and Tumor Growth by the RUNX1 Transcription FactorSemantic proximity Read ↗

Runx2 expression: A mesenchymal stem marker for cancerSemantic proximity Read ↗

<i>Runx1</i> and <i>Runx2</i> act in concert to suppress <i>Wnt/β-catenin</i> -driven mammary tumourigenesisSemantic proximity Read ↗

RUNX transcription factors at the interface of stem cells and cancer.Semantic proximity Read ↗

Defining a tissue stem cell‐driven Runx1/Stat3 signalling axis in epithelial cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.