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Article

Immunological responses during a virologically failing antiretroviral regimen are associated with in vivo synonymous mutation rates of HIV type-1 env.

Antiviral therapy - 1 Jan 2009

Mens Helene, Jørgensen Louise Bruun, Kronborg Gitte, Schønning Kristian, Benfield Thomas

Abstract excerpt

BACKGROUND: Little is known about the underlying causes of differences in immunological response to antiretroviral therapy during multidrug-resistant (MDR) HIV type-1 (HIV-1) infection. This study aimed to identify virological factors associated with immunological response during therapy failure. METHODS: Individuals with MDR HIV-1 receiving therapy for > or =3 months were included. CD4+ T-cell count slopes and...

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Share to Anti-Retroviral Agents
Share to Antiretroviral Therapy, Highly Active

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CD4 Lymphocyte Count

Share to env Gene Products, Human Immunodeficiency Virus

Share to HIV Infections

Share to pol Gene Products, Human Immunodeficiency Virus

Share to Treatment Failure

Source

Identifiers

PMID: 19474475

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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