Article
HIV type 1 fitness evolution in antiretroviral-experienced patients with sustained CD4+ T cell counts but persistent virologic failure.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 Sept 2005
Prado Julia G, Parkin Neil T, Clotet Bonaventura, Ruiz Lidia, Martinez-Picado Javier
Abstract excerpt
BACKGROUND: Over recent years, treatment guidelines for human immunodeficiency virus (HIV) infection have evolved from monotherapy to combination regimens that include > or = 3 active drugs, resulting in a sharp decrease in morbidity and mortality. In the present article, we evaluated changes in HIV type 1 viral fitness associated with the sequential introduction of antiretroviral treatment strategies in 4...
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