Article
Immunological and virological failure after antiretroviral therapy is associated with enhanced peripheral and thymic pathogenicity.
The Journal of infectious diseases - 15 Jun 2003
Solomon Ajantha, Cameron Paul U, Bailey Michael, Dunne Amanda L, Crowe Suzanne M, Hoy Jenny F, Lewin Sharon R
Abstract excerpt
T cell dynamics and viral genotype were studied in human immunodeficiency virus 1-infected individuals receiving antiretroviral therapy who were viremic and had either increasing (discordant immunological responders) or decreasing (nonresponders) CD4(+) T cell counts. A comparison was made with treated individuals who were not viremic and had increasing CD4(+) T cell counts (complete responders). Nonresponders...
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