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Article

The TLR7 7926A>G polymorphism is associated with susceptibility to systemic lupus erythematosus.

Molecular medicine reports - 1 Jul 2012

Tian Jing, Ma Yan, Li Jing, Cen Han, Wang De-Guang, Feng Chen-Chen, Li Ruo-Jie, Leng Rui-Xue, Pan Hai-Feng, Ye Dong-Qing

Abstract excerpt

Systemic lupus erythematosus (SLE) is a systemic autoimmune disorder that predominantly affects women of childbearing age, with a female-to-male ratio of approximately 9:1. Previous findings indicated that male cases of SLE were associated with Klinefelter's syndrome (47, XXY), whereas females with Turner's syndrome (45, X0) did not contract SLE. Additionally, duplicated Toll-like receptor 7 (TLR7) was found to...

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Source

Identifiers

PMID: 22505023
DOI: 10.3892/mmr.2012.865

Genes

TLR7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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