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Toll-like receptors in systemic lupus erythematosus: potential for personalized treatment

8 Dec 2014

Abstract excerpt

Systemic lupus erythematosus (SLE) is a complex autoimmune disease characterized by the loss of tolerance to self-nuclear antigens. The symptoms of SLE, progression of pathology and the array of autoantibodies present in the serum differ significantly from patient to patient, which calls for a personalized approach to treatment. SLE is polygenic and strongly influenced by gender, ethnicity, and environmental...

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PMID: 25538618
DOI: 10.3389/fphar.2014.00265

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