Article
Prevalence and clinical features of LRRK2 mutations in patients with Parkinson's disease in southern Spain.
European journal of neurology - 1 Aug 2009
Gao L, Gómez-Garre P, Díaz-Corrales F J, Carrillo F, Carballo M, Palomino A, Díaz-Martín J, Mejías R, Vime P J, López-Barneo J, Mir P
Abstract excerpt
BACKGROUND AND PURPOSE: Mutations in leucine-rich repeat kinase 2 (LRRK2) gene are associated with both familial and idiopathic Parkinson's disease (PD), whereas mutations in PARK2 (PARKIN) gene result in early onset recessive PD. Here, the objectives were to determine the frequency of LRRK2 G2019S and R1441G mutations in a PD population from southern Spain; to search for LRRK2 mutations in familial PD cases and...
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