Article
Genotyping the GGGCGG tandem repeat promoter polymorphism in the 5-lipoxygenase enzyme gene (ALOX5) by pyrosequencing assay.
Genetic testing and molecular biomarkers - 1 Jun 2009
Schentrup Anzeela M, Allayee Hooman, Lima John J, Johnson Julie A, Langaee Taimour Y
Abstract excerpt
AIMS: Efficient genotyping methods for many biologically significant repeat genetic polymorphisms, particularly in GC-rich regions of the genome, are limited. In particular, a short tandem repeat polymorphism [GGCGGG] in the promoter region of ALOX5 has been implicated as an important marker for inflammatory diseases. We developed a pyrosequencing assay to genotype the ALOX5 short tandem repeat polymorphism using...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.