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Article

Association of Sp1 tandem repeat polymorphism of ALOX5 with coronary artery disease in Indian subjects.

Clinical and translational science - 1 Oct 2012

Todur Seema P, Ashavaid Tester F

Abstract excerpt

Lipoxygenases have been implicated in the pathogenesis of coronary artery disease (CAD) for its potent proinflammatory role. The Sp1 addition/deletion polymorphism in promoter region of the 5-lipoxygenase gene (ALOX5) has been associated with increased risk of carotid atherosclerosis and myocardial infarction. To determine the role of this polymorphism in our population we performed a case-control-genetic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23067353
DOI: 10.1111/j.1752-8062.2011.00396.x
PMCID: PMC5439792

Genes

ALOX5
CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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