Article
XRCC2 and XRCC3 regulate the balance between short- and long-tract gene conversions between sister chromatids.
Molecular and cellular biology - 1 Aug 2009
Nagaraju Ganesh, Hartlerode Andrea, Kwok Amy, Chandramouly Gurushankar, Scully Ralph
Abstract excerpt
Sister chromatid recombination (SCR) is a potentially error-free pathway for the repair of DNA lesions associated with replication and is thought to be important for suppressing genomic instability. The mechanisms regulating the initiation and termination of SCR in mammalian cells are poorly understood. Previous work has implicated all the Rad51 paralogs in the initiation of gene conversion and the Rad51C/XRCC3...
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