Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A novel function of Aft1 in regulating ferrioxamine B uptake: Aft1 modulates Arn3 ubiquitination in Saccharomyces cerevisiae.

The Biochemical journal - 29 Jul 2009

Jeong Mi-Young, Kang Chang-Min, Kim Ji-Hyun, Heo Dong-Hyuk, Chang Miwha, Baek In-Joon, Ro Hyeon-Su, Choi Il-Dong, Kim Tae-Hyoung, Yun Cheol-Won

Abstract excerpt

Aft1 is a transcriptional activator in Saccharomyces cerevisiae that responds to iron availability and regulates the expression of genes in the iron regulon, such as FET3, FTR1 and the ARN family. Using a two-hybrid screen, we found that Aft1 physically interacts with the FOB (ferrioxamine B) transporter Arn3. This interaction modulates the ability of Arn3 to take up FOB. The interaction between Arn3 and Aft1 was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ceruloplasmin
Share to Deferoxamine

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Endoplasmic Reticulum

Share to Ferric Compounds

Share to Lysine

Share to Surface Plasmon Resonance

Share to Two-Hybrid System Techniques

Share to Ubiquitination

Source

Identifiers

PMID: 19469713
DOI: 10.1042/BJ20082399

Genes

SPR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A novel function of Aft1 in regulating ferrioxamine B uptake: Aft1 modulates Arn3 ubiquitination in Saccharomyces cerevisiae.PMID 19469713Read ↗

Aft2p, a novel iron-regulated transcription activator that modulates, with Aft1p, intracellular iron use and resistance to oxidative stress in yeast.Semantic proximity Read ↗

Aft1p and Aft2p mediate iron-responsive gene expression in yeast through related promoter elements.Semantic proximity Read ↗

A permease-oxidase complex involved in high-affinity iron uptake in yeast.Semantic proximity Read ↗

AFT1: a mediator of iron regulated transcriptional control in Saccharomyces cerevisiae.Semantic proximity Read ↗

Mechanism underlying the iron-dependent nuclear export of the iron-responsive transcription factor Aft1p in Saccharomyces cerevisiae.Semantic proximity Read ↗

Assembly, activation, and trafficking of the Fet3p.Ftr1p high affinity iron permease complex in Saccharomyces cerevisiae.Semantic proximity Read ↗

Siderophore-iron uptake in saccharomyces cerevisiae. Identification of ferrichrome and fusarinine transporters.Semantic proximity Read ↗

Iron-induced dissociation of the Aft1p transcriptional regulator from target gene promoters is an initial event in iron-dependent gene suppression.Semantic proximity Read ↗

A second iron-regulatory system in yeast independent of Aft1p.Semantic proximity Read ↗

The yeast iron regulon is induced upon cobalt stress and crucial for cobalt tolerance.Semantic proximity Read ↗

Zinc suppresses the iron-accumulation phenotype of Saccharomyces cerevisiae lacking the yeast frataxin homologue (Yfh1).Semantic proximity Read ↗

Proteomic profiling of the monothiol glutaredoxin Grx3 reveals its global role in the regulation of iron dependent processes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.