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Article

Proteomic profiling of the monothiol glutaredoxin Grx3 reveals its global role in the regulation of iron dependent processes.

PLoS genetics - 1 Jun 2020

Alkafeef Selma S, Lane Shelley, Yu Clinton, Zhou Tingting, Solis Norma V, Filler Scott G, Huang Lan, Liu Haoping

Abstract excerpt

Iron is an essential nutrient required as a cofactor for many biological processes. As a fungal commensal-pathogen of humans, Candida albicans encounters a range of bioavailable iron levels in the human host and maintains homeostasis with a conserved regulatory circuit. How C. albicans senses and responds to iron availability is unknown. In model yeasts, regulation of the iron homeostasis circuit requires...

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PMID: 32525871
DOI: 10.1371/journal.pgen.1008881
PMCID: PMC7319344

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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