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Article

Mechanism underlying the iron-dependent nuclear export of the iron-responsive transcription factor Aft1p in Saccharomyces cerevisiae.

Molecular biology of the cell - 1 Aug 2007

Ueta Ryo, Fujiwara Naoko, Iwai Kazuhiro, Yamaguchi-Iwai Yuko

Abstract excerpt

Aft1p is an iron-responsive transcriptional activator that plays a central role in maintaining iron homeostasis in Saccharomyces cerevisiae. Aft1p is regulated primarily by iron-induced shuttling of the protein between the nucleus and cytoplasm, but its nuclear import is not regulated by iron. He...

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PMID: 17538022
DOI: 10.1091/mbc.e06-11-1054
PMCID: PMC1949351

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17538022-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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