Article
Happyhour, a Ste20 family kinase, implicates EGFR signaling in ethanol-induced behaviors.
Cell - 29 May 2009
Corl Ammon B, Berger Karen H, Ophir-Shohat Galit, Gesch Julie, Simms Jeffrey A, Bartlett Selena E, Heberlein Ulrike
Abstract excerpt
The consequences of alcohol use disorders (AUDs) are devastating to individuals and society, yet few treatments are currently available. To identify genes regulating the behavioral effects of ethanol, we conducted a genetic screen in Drosophila and identified a mutant, happyhour (hppy), due to it...
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