Article
Alcohol interacts with genetic alteration of the Hippo tumor suppressor pathway to modulate tissue growth in Drosophila.
PloS one - 1 Jan 2013
Ilanges Anoj, Jahanshahi Maryam, Balobin Denis M, Pfleger Cathie M
Abstract excerpt
Alcohol-mediated cancers represent more than 3.5% of cancer-related deaths, yet how alcohol promotes cancer is a major open question. Using Drosophila, we identified novel interactions between dietary ethanol and loss of tumor suppressor components of the Hippo Pathway. The Hippo Pathway suppress...
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