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Article

Drosophila melanogaster, a genetic model system for alcohol research.

International review of neurobiology - 1 Jan 2003

Guarnieri Douglas J, Heberlein Ulrike

Abstract excerpt

In its natural environment, which consists of fermenting plant materials, the fruit fly Drosophila melanogaster encounters high levels of ethanol. Flies are well equipped to deal with the toxic effects of ethanol; they use it as an energy source and for lipid biosynthesis. The primary ethanol-metabolizing pathway in flies involves the enzymes alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH);...

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PMID: 12785288
DOI: 10.1016/s0074-7742(03)54006-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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