Article
A role for dynamin in triggering ethanol tolerance.
Alcoholism, clinical and experimental research - 1 Jan 2012
Krishnan Harish R, Al-Hasan Yazan M, Pohl Jascha B, Ghezzi Alfredo, Atkinson Nigel S
Abstract excerpt
BACKGROUND: A prevailing hypothesis is that the set of genes that underlie the endophenotypes of alcoholism overlap with those responsible for the addicted state. Functional ethanol tolerance, an endophenotype of alcoholism, is defined as a reduced response to ethanol caused by prior ethanol exposure. The neuronal origins of functional rapid tolerance are thought to be a homeostatic response of the nervous system...
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