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Article

rpoB nested PCR and sequencing for the early diagnosis of tuberculous meningitis and rifampicin resistance.

The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease - 1 Jun 2009

Huang H-J, Xiang D-R, Sheng J-F, Li J, Pan X-P, Yu H-Y, Sheng G-P, Li Lan-Juan

Abstract excerpt

SETTING: The prognosis of tuberculous meningitis (TBM) is linked to early diagnosis and prescription of adequate treatment. OBJECTIVE: To evaluate the efficacy of the rpoB nested polymerase chain reaction (PCR) and sequencing assay to detect and identify Mycobacterium tuberculosis complex (MTC) strains and strains resistant to rifampicin (RMP) in cerebrospinal fluid specimens (CSF) from patients with highly...

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PMID: 19460252

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