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Article

Novel mutation detection IN rpoB OF rifampicin-resistant Mycobacterium tuberculosis using pyrosequencing.

The Southeast Asian journal of tropical medicine and public health - 1 Jul 2014

Htike Min Pyar Kyi, Pitaksajjakul Pannamthip, Tipkrua Natthakan, Wongwit Waranya, Jintaridh Pornrutsami, Ramasoota Pongrama

Abstract excerpt

Tuberculosis (TB) remains a major global public health problem particularly severe in parts of Asia and Africa, where often it is present in HIV-AIDS patients. Although rifampicin-resistant (RIFr) TB is slow to emerge due to the low rate of mutation of its target leading to RIFE being a marker of TB that is already resistant to other anti-TB drugs, and such cases are prone to treatment failure. More than 95% of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25427352

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