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Article

Early detection of multidrug- and pre-extensively drug-resistant tuberculosis from smear-positive sputum by direct sequencing.

BMC infectious diseases - 24 Apr 2017

Chen Jun, Peng Peng, Du Yixiang, Ren Yi, Chen Lifeng, Rao Youyi, Wang Weihua

Abstract excerpt

BACKGROUND: Emergence of multidrug- and extensively drug-resistant tuberculosis (M/XDR-TB) is a major hurdle for TB control programs especially in developing countries like China. Resistance to fluoroquinolones is high among MDR-TB patients. Early diagnosis of MDR/pre-XDR-TB is essential for lowering transmission of drug-resistant TB and adjusting the treatment regimen. METHODS: Smear-positive sputum specimens...

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PMID: 28438132
DOI: 10.1186/s12879-017-2409-6
PMCID: PMC5402665

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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