Article
Rapid molecular detection of rifampicin resistance facilitates early diagnosis and treatment of multi-drug resistant tuberculosis: case control study.
PloS one - 9 Sept 2008
O'Riordan Philly, Schwab Uli, Logan Sarah, Cooke Graham, Wilkinson Robert J, Davidson Robert N, Bassett Paul, Wall Robert, Pasvol Geoffrey, Flanagan Katie L
Abstract excerpt
BACKGROUND: Multi-drug resistant tuberculosis (MDR-TB) is a major public health concern since diagnosis is often delayed, increasing the risk of spread to the community and health care workers. Treatment is prolonged, and the total cost of treating a single case is high. Diagnosis has traditionally relied upon clinical suspicion, based on risk factors and culture with sensitivity testing, a process that can take...
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