Article
Rapid prediction of rifampin susceptibility of Mycobacterium tuberculosis.
American journal of respiratory and critical care medicine - 1 Jun 1997
Ohno H, Koga H, Kuroita T, Tomono K, Ogawa K, Yanagihara K, Yamamoto Y, Miyamoto J, Tashiro T, Kohno S
Abstract excerpt
We evaluated the relationship between rifampin (RIF) susceptiblility and amino acid substitution in rpoB gene of Mycobacterium tuberculosis and the usefulness of rpoB gene sequencing in the rapid prediction of RIF susceptibility of M. tuberculosis in clinical specimens. A total of 76 genetic alte...
Topics
- Amino Acid Sequence
- Base Sequence
- DNA-Directed RNA Polymerases
- Forecasting
- Genes, Bacterial
- Humans
- Microbial Sensitivity Tests
- Molecular Sequence Data
- Mutation
- Mycobacterium tuberculosis
- Rifampin
- Time Factors
