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Article

Epigenetic footprint enables molecular risk stratification of hepatoblastoma with clinical implications

30 Mar 2020

Abstract excerpt

BACKGROUND & AIMS: Hepatoblastoma (HB) is a rare disease. Nevertheless, it is the predominant pediatric liver cancer, with limited therapeutic options for patients with aggressive tumors. Herein, we aimed to uncover the mechanisms of HB pathobiology and to identify new biomarkers and therapeutic targets in a move towards precision medicine for patients with advanced HB. METHODS: We performed a comprehensive...

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PMID: 32240714
DOI: 10.1016/j.jhep.2020.03.025

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