Article
Hepatoblastomas with carcinoma features represent a biological spectrum of aggressive neoplasms in children and young adults.
Journal of hepatology - 1 Oct 2022
Sumazin Pavel, Peters Tricia L, Sarabia Stephen F, Kim Hyunjae R, Urbicain Martin, Hollingsworth Emporia Faith, Alvarez Karla R, Perez Cintia R, Pozza Alice, Najaf Panah Mohammad Javad, Epps Jessica L, Scorsone Kathy, Zorman Barry, Katzenstein Howard, O'Neill Allison F, Meyers Rebecka, Tiao Greg, Geller Jim, Ranganathan Sarangarajan, Rangaswami Arun A, Woodfield Sarah E, Goss John A, Vasudevan Sanjeev A, Heczey Andras, Roy Angshumoy, Fisher Kevin E, Alaggio Rita, Patel Kalyani R, Finegold Milton J, López-Terrada Dolores H
Abstract excerpt
BACKGROUND & AIMS: Hepatoblastoma (HB) and hepatocellular carcinoma (HCC) are the predominant liver cancers in children, though their respective treatment options and associated outcomes differ dramatically. Risk stratification using a combination of clinical, histological, and molecular parameters can improve treatment selection, but it is particularly challenging for tumors with mixed histological features,...
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