Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genomic analysis of hepatoblastoma identifies distinct molecular and prognostic subgroups

24 Oct 2016

Abstract excerpt

Despite being the most common liver cancer in children, hepatoblastoma (HB) is a rare neoplasm. Consequently, few pretreatment tumors have been molecularly profiled, and there are no validated prognostic or therapeutic biomarkers for HB patients. We report on the first large-scale effort to profile pretreatment HBs at diagnosis. Our analysis of 88 clinically annotated HBs revealed three risk-stratifying molecular...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cholangiocarcinoma and Gallbladder Cancer Studies
Share to Hepatocellular Carcinoma Treatment and Prognosis
Share to Liver physiology and pathology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 27775819
DOI: 10.1002/hep.28888

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genomic analysis of hepatoblastoma identifies distinct molecular and prognostic subgroupsPMID 27775819Read ↗

Hepatoblastoma: an investigation of diagnostic, prognostic, and therapeutic gene targets and biomarkers.Semantic proximity Read ↗

Hepatoblastoma state of the art: pathology, genetics, risk stratification, and chemotherapy.Semantic proximity Read ↗

Hepatoblastomas with carcinoma features represent a biological spectrum of aggressive neoplasms in children and young adults.Semantic proximity Read ↗

Single‐cell transcriptomics uncovers cellular architecture and developmental trajectories in hepatoblastomaSemantic proximity Read ↗

DNA methylation as a key epigenetic player for hepatoblastoma characterizationSemantic proximity Read ↗

Mutational signature, cancer driver genes mutations and transcriptomic subgroups predict hepatoblastoma survival.Semantic proximity Read ↗

Hepatoblastoma: current understanding, recent advances, and controversiesSemantic proximity Read ↗

Integrated multiomics analysis of hepatoblastoma unravels its heterogeneity and provides novel druggable targetsSemantic proximity Read ↗

Genetic and epigenetic basis of hepatoblastoma diversity.Semantic proximity Read ↗

Gene expression profiling reveals signatures characterizing histologic subtypes of hepatoblastoma and global deregulation in cell growth and survival pathwaysSemantic proximity Read ↗

Epigenetic footprint enables molecular risk stratification of hepatoblastoma with clinical implicationsSemantic proximity Read ↗

Biology of childhood hepatoblastoma and the search for novel treatmentsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.