Article
Up-regulation of the inflammatory-reparative phenotype in human prostate carcinoma.
The Prostate - 1 Aug 2009
Ravenna Linda, Sale Patrizio, Di Vito Maura, Russo Andrea, Salvatori Luisa, Tafani Marco, Mari Emanuela, Sentinelli Steno, Petrangeli Elisa, Gallucci Michele, Di Silverio Franco, Russo Matteo A
Abstract excerpt
BACKGROUND: Recent studies have underlined the role of tumor cells in the endogenous synthesis of pro-inflammatory molecules. We tested whether malignant progression in prostate cancer was associated with the activation of a phenotype typical of the innate immune system. METHODS: The expression of a set of molecules involved in tissue inflammation and repair was measured by real-time PCR and Western blot analysis...
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