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Article

Distinct phenotypes of human prostate cancer cells associate with different adaptation to hypoxia and pro-inflammatory gene expression.

PloS one - 1 Jan 2014

Ravenna Linda, Principessa Lorenzo, Verdina Alessandra, Salvatori Luisa, Russo Matteo Antonio, Petrangeli Elisa

Abstract excerpt

Hypoxia and inflammation are strictly interconnected both concurring to prostate cancer progression. Numerous reports highlight the role of tumor cells in the synthesis of pro-inflammatory molecules and show that hypoxia can modulate a number of these genes contributing substantially to the increase of cancer aggressiveness. However, little is known about the importance of the tumor phenotype in this process. The...

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Share to Cell Hypoxia

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Line, Tumor

Share to Gene Expression Regulation, Neoplastic

Share to Hypoxia-Inducible Factor 1, alpha Subunit

Share to NF-kappa B

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Source

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Identifiers

PMID: 24801981
DOI: 10.1371/journal.pone.0096250
PMCID: PMC4011733

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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