Article
Genetic polymorphisms of RANTES, IL1-A, MCP-1 and TNF-A genes in patients with prostate cancer.
BMC cancer - 19 Dec 2008
Sáenz-López Pablo, Carretero Rafael, Cózar José Manuel, Romero José Maria, Canton Julia, Vilchez José Ramón, Tallada Miguel, Garrido Federico, Ruiz-Cabello Francisco
Abstract excerpt
BACKGROUND: Inflammation has been implicated as an etiological factor in several human cancers, including prostate cancer. Allelic variants of the genes involved in inflammatory pathways are logical candidates as genetic determinants of prostate cancer risk. The purpose of this study was to investigate whether single nucleotide polymorphisms of genes that lead to increased levels of pro-inflammatory cytokines and...
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