Article
Inflammation in prostate carcinogenesis.
Nature reviews. Cancer - 1 Apr 2007
De Marzo Angelo M, Platz Elizabeth A, Sutcliffe Siobhan, Xu Jianfeng, Grönberg Henrik, Drake Charles G, Nakai Yasutomo, Isaacs William B, Nelson William G
Abstract excerpt
About 20% of all human cancers are caused by chronic infection or chronic inflammatory states. Recently, a new hypothesis has been proposed for prostate carcinogenesis. It proposes that exposure to environmental factors such as infectious agents and dietary carcinogens, and hormonal imbalances lead to injury of the prostate and to the development of chronic inflammation and regenerative 'risk factor' lesions,...
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