Article

Functional characterization of three novel candidate biomarkers and therapeutic targets for prostate cancer

2010-01-01

Abstract excerpt

Anterior gradient-2 (AGR2), S100A4, and osteopontin (OPN) play important roles in malignant progression of breast cancer. Their possible involvement in prostate cancer had not been full explored previously. The aim of this study was to investigate the expression status of these genes and their diagnostic and prognostic significance in prostate cancer. The possibility of using these candidate genes as targets to su...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 65f55bca-e4d7-5c56-9041-397fc14f7e0d
DOI: 10.17638/03006344

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Functional characterization of three novel candidate biomarkers and therapeutic targets for prostate cancerDOI 10.17638/03006344Read

Prostate cancer cell phenotypes based on AGR2 and CD10 expression.Semantic proximity Read

Bioinformatics Analysis to Identify MEG3-hsa-miR-222-3p-NRG1/CLVS2 Axis as a Prognostic Biomarker in Prostate CancerSemantic proximity Read

Anterior gradient 2 (AGR2): blood-based biomarker elevated in metastatic prostate cancer associated with the neuroendocrine phenotype.Semantic proximity Read

The potential prognostic value of Cartilage acidic protein 1 and secretoglobin family 1D member 1 in prostate cancerSemantic proximity Read

Annexin A2 positively contributes to the malignant phenotype and secretion of IL-6 in DU145 prostate cancer cells.Semantic proximity Read

Proteomic analysis of normal and malignant prostate tissue to identify novel proteins lost in cancerSemantic proximity Read

Distinctive gene expression of prostatic stromal cells cultured from diseased versus normal tissuesSemantic proximity Read

PKA-driven SPP1 activation as a novel mechanism connecting the bone microenvironment to prostate cancer progressionSemantic proximity Read

Integrative analysis of AGR2 based on data mining reveals new insights in breast cancerSemantic proximity Read

Androgen receptor and osteoglycin gene expression predicting prognosis of metastatic prostate cancerSemantic proximity Read

Proteomic Characterization of Primary and Metastatic Prostate Cancer Reveals Reduced Proteinase Activity in Aggressive TumorsSemantic proximity Read

Differentially Expressed Androgen-Regulated Genes in Androgen-Sensitive Tissues Reveal Potential Biomarkers of Early Prostate CancerSemantic proximity Read