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Article

Deletion of LCE3C and LCE3B genes at PSORS4 does not contribute to susceptibility to psoriatic arthritis in German patients.

Annals of the rheumatic diseases - 1 May 2010

Hüffmeier Ulrike, Estivill Xavier, Riveira-Munoz Eva, Traupe Heiko, Wendler Jörg, Lohmann Jörg, Böhm Beate, Burkhardt Harald, Reis André

Abstract excerpt

INTRODUCTION: Psoriasis susceptibility locus 4 (PSORS4) is a susceptibility locus for psoriasis vulgaris (PsV), a common inflammatory, hyperproliferative skin disorder. Recently, a deletion of 2 late cornified envelope (LCE) genes within epidermal differentiation complex on chromosome 1 was shown to be enriched in 1426 patients with PsV, suggesting compromised barrier function in deletion carriers. This genetic...

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Identifiers

PMID: 19439430
DOI: 10.1136/ard.2009.108951
PMCID: PMC2925148

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Deletion of LCE3C and LCE3B genes at PSORS4 does not contribute to susceptibility to psoriatic arthritis in German patients.PMID 19439430Read ↗

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