Article
Deletion of late cornified envelope genes, LCE3C_LCE3B-del, is not associated with psoriatic arthritis in Tunisian patients.
Molecular biology reports - 1 Jun 2014
Chiraz Bouchlaka Souissi, Myriam Ammar, Ines Zarra, Catherine Jordan, Fatma Bouazizi, Ilhem Cheour, Raoudha Tekaya, Hela Zeglaoui, Hela Fourati, Elyes Bouajina, Nejib Doss, Cindy Helms, Amel Elgaaied, Slaheddine Sellami
Abstract excerpt
A deletion of two genes from the late cornified envelope (LCE), LCE3B and LCE3C within epidermal differentiation complex on chromosome 1 was shown to be associated with both psoriasis and psoriatic arthritis (PsA) in several populations. To assess whether this deletion may contribute to the genetic predisposition to PsA in Tunisia, a total of 73 patients with PsA and 120 healthy matched controls were screened for...
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