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Article

Lower levels of ADAMTS13 are associated with cardiovascular disease in young patients.

Atherosclerosis - 1 Nov 2009

Bongers T N, de Bruijne E L E, Dippel D W J, de Jong A J, Deckers J W, Poldermans D, de Maat M P M, Leebeek F W G

Abstract excerpt

ADAMTS13 may play a role in arterial thrombosis by cleaving the highly active and thrombogenic ultralarge Von Willebrand Factor (VWF) multimers into less active VWF multimers. The aim was to investigate the relationship between plasma levels of ADAMTS13, VWF and genetic variation in the ADAMTS13 gene with cardiovascular disease. We performed a case-control study in 374 patients with a first-ever arterial...

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Source

Identifiers

PMID: 19439298
DOI: 10.1016/j.atherosclerosis.2009.04.013

Genes

ADAMTS13
VWF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Lower levels of ADAMTS13 are associated with cardiovascular disease in young patients.PMID 19439298Read ↗

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