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Article

Role of ADAMTS13, VWF and F8 genes in deep vein thrombosis.

PloS one - 1 Jan 2021

Pagliari Maria Teresa, Cairo Andrea, Boscarino Marco, Mancini Ilaria, Pappalardo Emanuela, Bucciarelli Paolo, Martinelli Ida, Rosendaal Frits R, Peyvandi Flora

Abstract excerpt

BACKGROUND: We previously described the association between rare ADAMTS13 single nucleotide variants (SNVs) and deep vein thrombosis (DVT). Moreover, DVT patients with at least one rare ADAMTS13 SNV had a lower ADAMTS13 activity than non-carriers. AIMS: To confirm ADAMTS13 variants association with DVT and reduced plasma ADAMTS13 activity levels in a larger population. To investigate the role of VWF and F8...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34662354
DOI: 10.1371/journal.pone.0258675
PMCID: PMC8523043

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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