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Article

Genetic determinants of von Willebrand factor levels and activity in relation to the risk of cardiovascular disease: a review.

Journal of thrombosis and haemostasis : JTH - 1 May 2011

van Schie M C, van Loon J E, de Maat M P M, Leebeek F W G

Abstract excerpt

It is well established that high plasma von Willebrand factor (VWF) levels are associated with an increased risk of arterial thrombosis, including myocardial infarction and ischemic stroke. As plasma VWF levels are, to a large extent, genetically determined, numerous association studies have been performed to assess the effect of genetic variability in the VWF gene (VWF) on VWF antigen and activity levels, and on...

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Source

Identifiers

PMID: 21342431
DOI: 10.1111/j.1538-7836.2011.04243.x

Genes

VWF
ABO

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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