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Article

Mannose binding lectin acute phase activity in patients with severe infection.

Journal of clinical immunology - 1 Jul 2005

Dean M M, Minchinton R M, Heatley S, Eisen D P

Abstract excerpt

Mannose Binding Lectin (MBL) is a liver derived, circulating plasma protein that plays a pivotal role in innate immunity. MBL functions as a pathogen recognition molecule, opsonising organisms and initiating the complement cascade. MBL deficiency arising from mutations and promoter polymorphisms in the MBL2 gene is common and has been associated with risk, severity, and frequency of infection in a number of...

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Source

Identifiers

PMID: 16133991
DOI: 10.1007/s10875-005-4702-1

Genes

MBL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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