Article
p53 in recombination and repair.
Cell death and differentiation - 1 Jun 2006
Gatz S A, Wiesmüller L
Abstract excerpt
Convergent studies demonstrated that p53 regulates homologous recombination (HR) independently of its classic tumour-suppressor functions in transcriptionally transactivating cellular target genes that are implicated in growth control and apoptosis. In this review, we summarise the analyses of the involvement of p53 in spontaneous and double-strand break (DSB)-triggered HR and in alternative DSB repair routes....
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