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Article

The human GLUD2 glutamate dehydrogenase: localization and functional aspects.

Neurochemistry international - 1 Jan 2000

Zaganas Ioannis, Kanavouras Konstantinos, Mastorodemos Vasileios, Latsoudis Helen, Spanaki Cleanthe, Plaitakis Andreas

Abstract excerpt

In all mammals, glutamate dehydrogenase (GDH), an enzyme central to the metabolism of glutamate, is encoded by a single gene (GLUD1 in humans) which is expressed widely (housekeeping). Humans and other primates also possess a second gene, GLUD2, which encodes a highly homologous GDH isoenzyme (hGDH2) expressed predominantly in retina, brain and testis. There is evidence that GLUD1 was retro-posed <23 million...

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Source

Identifiers

PMID: 19428807
DOI: 10.1016/j.neuint.2009.03.001

Genes

GLUD2
GLUD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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