Article
Important role of Ser443 in different thermal stability of human glutamate dehydrogenase isozymes.
FEBS letters - 26 Mar 2004
Yang Seung-Ju, Huh Jae-Wan, Hong Hea-Nam, Kim Tae Ue, Cho Sung-Woo
Abstract excerpt
Molecular biological studies confirmed that two glutamate dehydrogenase isozymes (hGDH1 and hGDH2) of distinct genetic origin are expressed in human tissues. hGDH1 is heat-stable and expressed widely, whereas hGDH2 is heat-labile and specific for neural and testicular tissues. A selective deficie...
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