The RAD9-dependent gene trans-activation is required for excision repair of active genes but not for repair of non-transcribed DNA.

doi:10.1016/j.mrfmmm.2009.01.008

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

The RAD9-dependent gene trans-activation is required for excision repair of active genes but not for repair of non-transcribed DNA.

Mutation research - 26 Apr 2009

Al-Moghrabi Nisreen M, Al-Sharif Ibtehaj S, Aboussekhra Abdelilah

Abstract excerpt

The Saccharomyces cerevisiae RAD9 and RAD24 are two cell cycle checkpoint genes required for UV-dependent up-regulation of a battery of genes involved in different metabolic pathways. RAD9 is also implicated in nucleotide excision repair (NER); however, its precise role is still unclear. For the present study, we made use of the high-resolution primer extension technique to show that the RAD9-deleted cells are...

Topics

Cell Cycle Proteins
Cycloheximide
DNA Repair
DNA, Fungal
Fungal Proteins
Gene Expression Regulation, Fungal
Genes, Fungal
Intracellular Signaling Peptides and Proteins
Mutation
Promoter Regions, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Protein Biosynthesis

Pyrimidine Dimers

Saccharomyces cerevisiae

Transcription, Genetic

Transcriptional Activation

Ultraviolet Rays

Source

Open in PubMed

Identifiers

PMID: 19428371
DOI: 10.1016/j.mrfmmm.2009.01.008

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The RAD9-dependent gene trans-activation is required for excision repair of active genes but not for repair of non-transcribed DNA.PMID 19428371Read ↗

Characterization of RAD9 of Saccharomyces cerevisiae and evidence that its function acts posttranslationally in cell cycle arrest after DNA damage.Semantic proximity Read ↗

Rad26, the transcription-coupled repair factor in yeast, is required for removal of stalled RNA polymerase-II following UV irradiation.Semantic proximity Read ↗

Characterization and expression of RAD4 gene involved in nucleotide excision repair of UV-damaged Saccharomyces cerevisiae.Semantic proximity Read ↗

DNA repair gene RAD3 of S. cerevisiae is essential for transcription by RNA polymerase II.Semantic proximity Read ↗

RAD9, RAD24, RAD16 and RAD26 are required for the inducible nucleotide excision repair of UV-induced cyclobutane pyrimidine dimers from the transcribed and non-transcribed regions of the Saccharomyces cerevisiae MFA2 gene.Semantic proximity Read ↗

Dissecting transcription-coupled and global genomic repair in the chromatin of yeast GAL1-10 genes.Semantic proximity Read ↗

A role for checkpoint kinase-dependent Rad26 phosphorylation in transcription-coupled DNA repair in Saccharomyces cerevisiae.Semantic proximity Read ↗

Characterization of a novel DNA damage-inducible gene of Saccharomyces cerevisiae, DIN7, which is a structural homolog of the RAD2 and RAD27 DNA repair genes.Semantic proximity Read ↗

The yeast RAD7 and RAD16 genes are required for postincision events during nucleotide excision repair. In vitro and in vivo studies with rad7 and rad16 mutants and purification of a Rad7/Rad16-containing protein complex.Semantic proximity Read ↗

Functionally distinct nucleosome-free regions in yeast require Rad7 and Rad16 for nucleotide excision repair.Semantic proximity Read ↗

Rad33, a new factor involved in nucleotide excision repair in Saccharomyces cerevisiae.Semantic proximity Read ↗

Identification and characterization of the rhp23(+) DNA repair gene in Schizosaccharomyces pombe.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.