Article
The RAD9-dependent gene trans-activation is required for excision repair of active genes but not for repair of non-transcribed DNA.
Mutation research - 26 Apr 2009
Al-Moghrabi Nisreen M, Al-Sharif Ibtehaj S, Aboussekhra Abdelilah
Abstract excerpt
The Saccharomyces cerevisiae RAD9 and RAD24 are two cell cycle checkpoint genes required for UV-dependent up-regulation of a battery of genes involved in different metabolic pathways. RAD9 is also implicated in nucleotide excision repair (NER); however, its precise role is still unclear. For the present study, we made use of the high-resolution primer extension technique to show that the RAD9-deleted cells are...
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