Article
The yeast RAD7 and RAD16 genes are required for postincision events during nucleotide excision repair. In vitro and in vivo studies with rad7 and rad16 mutants and purification of a Rad7/Rad16-containing protein complex.
The Journal of biological chemistry - 6 Nov 1998
Reed S H, You Z, Friedberg E C
Abstract excerpt
In eukaryotes, nucleotide excision repair (NER) is a complex reaction requiring multiple proteins. In the yeast Saccharomyces cerevisiae, two of these proteins, Rad7 and Rad16, are specifically involved in the removal of lesions from transcriptionally silent regions of the genome in vivo. Extract...
Topics
- Adenosine Triphosphatases
- Base Sequence
- DNA
- DNA Primers
- DNA Repair
- DNA-Binding Proteins
- Fungal Proteins
- Genetic Complementation Test
- Mutation
- Plasmids
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins